Bioinformatics for glycomics: Status, methods, requirements and perspectives

Phage Display Informatics

1 Center of Bioinformatics (COBI), Key Laboratory for NeuroInformation of Ministry of Education, University of Electronic Science and Technology of China, Chengdu 610054, China 2Department of Chemistry and Alberta Glycomics Centre, University of Alberta, Edmonton, AB, Canada T6G 2G2 3National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun...

Using Bioinformatics to Spearhead the Glycomics Revolution

The carbohydrate sequence markup language (CabosML): an XML description of carbohydrate structures

UNLABELLED Bioinformatics resources for glycomics are very poor as compared with those for genomics and proteomics. The complexity of carbohydrate sequences makes it difficult to define a common language to represent them, and the development of bioinformatics tools for glycomics has not progressed. In this study, we developed a carbohydrate sequence markup language (CabosML), an XML descriptio...

GlycoRDF: an ontology to standardize glycomics data in RDF

MOTIVATION Over the last decades several glycomics-based bioinformatics resources and databases have been created and released to the public. Unfortunately, there is no common standard in the representation of the stored information or a common machine-readable interface allowing bioinformatics groups to easily extract and cross-reference the stored information. RESULTS An international group...

GlycoPattern: a web platform for glycan array mining

UNLABELLED GlycoPattern is Web-based bioinformatics resource to support the analysis of glycan array data for the Consortium for Functional Glycomics. This resource includes algorithms and tools to discover structural motifs, a heatmap visualization to compare multiple experiments, hierarchical clustering of Glycan Binding Proteins with respect to their binding motifs and a structural search fe...